OPPS Billing in Chemotherapy Manager The CureMD application and Chemotherapy Manager now features Hospital Outpatient Prospective Payment System (OPPS). Enabling practices to bill patients under OPPS for applicable drugs and services. What are Location Based Modifiers? How to Identify an OPPS Drug on Practice Preferred NDC Screen? How to Ensure Location Based Modifiers be Carried Over to eSuperbill? What are OPPS Option in Billing Configuration? How to Use OPPS Modifiers on Drug Administration Strip? What is the Use of Special 99 Modifier?